Posttranslational modification of Birch and Ragweed allergen proteins by common gas phase pollutants, NO2 and O3

Marliyyah A. Mahmood, Francis D. Pope and William J. Bloss.

The impact of air pollution on the environment and human health is a vital concern to the world. Air pollution exacerbates several medical conditions such as allergies; in particular hay fever and asthma. The global incidence of hay fever has been rising for decades; however, the underlying reasons behind this rise remain unclear. It is hypothesized that the exposure of pollen to common gas phase pollutants, such as nitrogen dioxide (NO2) and ozone (O3), increases the allergenicity of the pollen and thus increases hay fever incidence. Since atmospheric pollutants tend to have greater concentrations within urban areas (in particular NO2) the hypothesis suggests that greater allergenicity should occur in urban areas. Indeed, several studies do suggest higher hay fever incidence within urban areas compared to rural areas.

Join today to view and download the full abstract/presentation