Adequate ventilation is necessary to maintain thermal comfort and remove indoor air pollutant concentrations. Indoor pollutant concentrations vary considerably depending on occupants’ behaviour patterns, building characteristics and meteorological parameters and seasonal effects. A recently modified model, IAPPEM, simulates both thermal comfort and indoor air pollutants concentrations, resulting in a time-series analysis of both parameters. This allows simulations of variations in occupants’ behavioural patterns, household characteristics, natural and mechanical ventilation.