Looking Back and Looking Ahead: Developments in Aerosol Medicine over the last 50 Years –
Devices, Drug and Detection of Disease
Myrna B Dolovich, B.Eng., P.Eng
Faculty of Health Sciences, McMaster University/St Joseph`s Healthcare Hamilton,
50 Charlton Ave E, Hamilton, Ontario/ L8N 4A6, Canada
Introduction
Over the years, advances in technology, coupled with discovery in physiology, physics and pharmaceutics have been applied extensively to the delivery of aerosol therapy and respiratory medicine. Innovations in the design of all categories of aerosol drug delivery devices (ADDD) and also pharmaceutical formulations have resulted in highly efficient delivery systems as well as tailored aerosols. Dual and triple combination therapies are now widely prescribed in portable inhalers for patients with asthma and COPD. By manipulating particle size and inhalation variables, the possibilities of providing targeted treatments to specific regions of the lung may also be feasible, enhancing treatment for patients with various respiratory and non-respiratory diseases