Impact of real time feedback from inhalation devices on patient satisfaction and adherence

Bernhard Müllinger¹, Tobias Kolb¹ & Tobias Gessler²

¹Vectura GmbH, Robert-Koch-Allee 29, Gauting, 82131, Germany

²University of Giessen and Marburg Lung Center, Klinikstraße 33, Gießen, 35392, Germany

Summary

Inhaler use errors and poor compliance are the most common reasons for failures in inhalation treatments. Correct inhaler technique is key for effective treatment with inhalation devices, but many patients fail to use inhalation devices correctly even after training and education. Inhalation devices, which guide patients on correct inhalation technique by design may reduce inhalation errors resulting in a higher patient satisfaction, better adherence and improved treatment outcomes. Smart nebulisers such as Breelib™ and AKITA^® JET improve inhalation technique by providing real-time feedback to patients on correct inhalation steps. Both inhalers guide patients to an optimum inhalation inspiratory flow rate and volume and help them to avoid errors to achieve an effective delivery of aerosols to periphery of the lungs.  This analysis assesses patient satisfaction and treatment compliance from two different studies. Patient satisfaction and ease of use of the device was assessed in a study in PAH patients inhaling Iloprost via Breelib™, a novel smart nebuliser. The study showed that patients were highly satisfied with the use of Breelib™. Patients found that the device was easy to use and the treatment time per treatment session was reduced by 8.3 min when using Breelib compared to a standard device. In a second study treatment compliance was assessed in patients with severe asthma being treated with budesonide inhalation suspension via AKITA JET. Total dose compliance over all patients was 82%. Together, these findings suggest that smart nebulisers that guide patients on correct inhalation technique and monitor treatment adherence, can improve patient satisfaction, which may result in better adherence and improved clinical outcomes in patients.